Rabbit Monoclonal Development by B Cell Cloning

Rabbit monoclonal antibodies are developed directly from isolated B cells of immunized animals without the use of hybridomas. The technology allows the sampling of much larger B cell repertoire for the screening and selection of high quality antibodies to suite customers’ application needs. Antigen-specific B cells are cultured in multi-well plates and supernatant samples screened to identify desired antibodies. The cDNAs encoding the H and L chains are isolated and expressed in a mammalian expression system for batch-to-batch consistency and higher yield. Expression-ready cDNA constructs and complete sequences are provided to customers upon project completion, enabling customers to produce the antibodies in-house and to protect the intellectual property.

Highlights of Excel BioPharm Rabbit Monoclonal Services -

  • Robust technology to generate monoclonal antibodies with high affinity and high specificity​


  • Customers having exclusive ownership to delivered clones, with no licensing/royalties due to Service Provider​


  • ​​Win-win deal structure -- all service work is done near cost to limit Customer’s expense to bare minimum; Service Provider and Customer are true partners throughout the project, and Excel BioPharm is profitable if and only if the desired antibody clones are successfully generated.

Please contact us today for your custom antibody projects  -  info@excelbiopharm.com